RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; enzyme-linked immunosorbent assay etc.
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MiR-155 regulates high glucose-induced cardiac fibrosis via the TGF-B signaling pathway
Year
2016
Function
miR-155 deficiency could prevent cardiac fibrosis induced by diabetes in mice and also that attenuated collagen synthesis is induced by high glucose (HG) in cardiac fibrosis.miR-155 regulated cardiac fibrosis via the TGF-beta1-smad 2 signaling pathway.